The Bronte Streak House and Grill in Banbridge hosted a coffee morning with lots of wonderful treats to launch the CLIC Sargent logo on the lorries.
McCallister Transport is a family run business specialising in road haulage, contractors, warehousing and shipping facilities.
Operator Jonathan McCallister said: "I have two small children who are my world and I don’t know what I would do if anything was to happen to them.
"The lady in B&Q, Newry told me about the work of CLIC Sargent Northern Ireland.
"I really did not know about the impact childhood cancer had on families and the distances families in Northern Ireland have to travel to get to the Royal Belfast Hospital for Sick Children or City Hospital."
CLIC Sargent Fundraising Manager Fiona McCann said: "We are so grateful of McCallister Transport to support CLIC Sargent by putting our logos on their lorries.
"It is such a great opportunity for awareness raising, especially when they transport all over the UK. So thumbs up and beep beep to McCallister Transport when you see them on the roads."